8ZYO: Cryo-EM Structure of astemizole-bound hERG Channel

PDB ID: 8ZYODownload
MMDB ID: 252521
PDB Deposition Date: 2024/6/18
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.29  Å
Source Organism:
Similar Structures:
Biological Unit for 8ZYO: tetrameric; determined by author
Molecular Components in 8ZYO
Label Count Molecule
Proteins (4 molecules)
4
Potassium Voltage-gated Channel Subfamily H Member 2
(Gene symbol: KCNH2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303