8ZR5: Cryo-EM Structure of GPR119-Gs-Firuglipel complex

PDB ID: 8ZR5Download
MMDB ID: 248676
PDB Deposition Date: 2024/6/4
Updated in MMDB: 2025/08
Experimental Method:
electron microscopy
Resolution: 3.31  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8ZR5: pentameric; determined by author
Molecular Components in 8ZR5
Label Count Molecule
Proteins (5 molecules)
1
Guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Nanobody 35
Molecule annotation
1
Glucose-dependent Insulinotropic Receptor
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
Unknown
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303