8ZMB: Crystal Structure of the first bromodomain of human BRD4 BD1 in complex with the inhibitor Y13195

PDB ID: 8ZMBDownload
MMDB ID: 256505
PDB Deposition Date: 2024/5/22
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.79  Å
Source Organism:
Similar Structures:
Biological Unit for 8ZMB: monomeric; determined by author
Molecular Components in 8ZMB
Label Count Molecule
Protein (1 molecule)
1
Brd4_human
(Gene symbol: BRD4)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
Unknown
2
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
2
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303