8Z8X: Cryo-EM structure of Thogoto virus polymerase in a transcription initiation conformation

PDB ID: 8Z8XDownload
MMDB ID: 247733
PDB Deposition Date: 2024/4/22
Updated in MMDB: 2025/07
Experimental Method:
electron microscopy
Resolution: 3.06  Å
Source Organism:
Similar Structures:
Biological Unit for 8Z8X: pentameric; determined by author and by software
Molecular Components in 8Z8X
Label Count Molecule
Proteins (3 molecules)
1
Polymerase Acidic Protein
(Gene symbol: THOV_s3gp1)
Molecule annotation
1
RNA-directed RNA Polymerase Catalytic Subunit
(Gene symbol: THOV_s2gp1)
Molecule annotation
1
Polymerase Basic Protein 2
(Gene symbol: THOV_s1gp1)
Molecule annotation
Nucleotides(2 molecules)
1
RNA (5'-r(*ap*gp*ap*gp*ap*ap*ap*up*cp*ap*ap*gp*gp*cp*ap*gp*up*u)-3')
Molecule annotation
1
RNA (5'-r(*gp*ap*cp*up*gp*cp*cp*up*gp*up*up*up*up*up*gp*cp*u)-3')
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTERPHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303