8Z69: Crystal Structure of the second bromodomain of human BRD2 BD2 in complex with the inhibitor Y13195

PDB ID: 8Z69Download
MMDB ID: 256486
PDB Deposition Date: 2024/4/18
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.77  Å
Source Organism:
Similar Structures:
Biological Unit for 8Z69: tetrameric; determined by author
Molecular Components in 8Z69
Label Count Molecule
Proteins (4 molecules)
4
Brd2_human
(Gene symbol: BRD2)
Molecule annotation
Chemicals and Non-standard biopolymers (28 molecules)
1
4
Unknown
2
10
FORMIC ACIDFORMIC ACID
3
4
GLYCEROLGLYCEROL
4
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
2
SODIUM IONSODIUM ION
6
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303