8YWQ: Crystal structure of the Fab fragment of the anti-IL-6 antibody I9H in complex with a domain-swapped IL-6 dimer

PDB ID: 8YWQDownload
MMDB ID: 254680
PDB Deposition Date: 2024/3/31
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.51  Å
Source Organism:
Similar Structures:
Biological Unit for 8YWQ: hexameric; determined by author
Molecular Components in 8YWQ
Label Count Molecule
Proteins (6 molecules)
2
Heavy Chain of the FAB Fragment of Anti-il-6 Antibody I9H
Molecule annotation
2
Light Chain of the FAB Fragment of Anti-il-6 Antibody I9H
Molecule annotation
2
Interleukin-6
(Gene symbol: IL6)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303