National Center for
Biotechnology Information

8YUU: Cryo-EM structure of the histamine-bound H3R-Gi complex

PDB ID:

MMDB ID:

247994

PDB Deposition Date:

2024/3/27

Updated in MMDB:

2024/07

Experimental Method:

electron microscopy

Resolution:

2.7 Å

Source Organism:

Mus musculus▼

Taxonomy	Molecule
Mus musculus	S
Homo sapiens	R, A, B, G

Similar Structures:

Biological Unit for 8YUU: pentameric; determined by author

Molecular Components in 8YUU
Label	Count	Molecule
Proteins (5 molecules)
R	1	Histamine H3 Receptor
A	1	Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
B	1	Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
G	1	Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
S	1	Scfv16
Chemicals and Non-standard biopolymers (2 molecules)
1	1	HISTAMINE
2	1	CHOLESTEROL

* Click molecule labels to explore molecular sequence information.

Citing MMDB