8YUT: Cryo-EM structure of the amthamine-bound H2R-Gs complex

PDB ID: 8YUTDownload
MMDB ID: 247993
PDB Deposition Date: 2024/3/27
Updated in MMDB: 2024/07
Experimental Method:
electron microscopy
Resolution: 2.7  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8YUT: pentameric; determined by author
Molecular Components in 8YUT
Label Count Molecule
Proteins (5 molecules)
1
Guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Nanobody-35
Molecule annotation
1
Histamine H2 Receptor
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
Unknown
2
1
CHOLESTEROLCHOLESTEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303