8YN5: Cryo-EM structure of histamine H3 receptor in complex with histamine and Gi

PDB ID: 8YN5Download
MMDB ID: 253329
PDB Deposition Date: 2024/3/10
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 2.7  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8YN5: pentameric; determined by author and by software
Molecular Components in 8YN5
Label Count Molecule
Proteins (5 molecules)
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Antibody Fragment Scfv16
Molecule annotation
1
Histamine H3 Receptor
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
HISTAMINEHISTAMINE
2
5
CHOLESTEROLCHOLESTEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303