8Y2G: Cryo-EM structure of human dopamine transporter in complex with methylphenidate

PDB ID: 8Y2GDownload
MMDB ID: 251127
PDB Deposition Date: 2024/1/25
Updated in MMDB: 2025/09
Experimental Method:
electron microscopy
Resolution: 2.83  Å
Source Organism:
Similar Structures:
Biological Unit for 8Y2G: monomeric; determined by author
Molecular Components in 8Y2G
Label Count Molecule
Protein (1 molecule)
1
Sodium-dependent Dopamine Transporter
(Gene symbol: SLC6A3)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
Unknown
2
2
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
3
1
CHLORIDE IONCHLORIDE ION
4
2
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303