8Y0C: Crystal structure of FnCas12a in complex with pre-crRNA and 18nt target DNA

PDB ID: 8Y0CDownload
MMDB ID: 257505
PDB Deposition Date: 2024/1/22
Updated in MMDB: 2025/02
Experimental Method:
x-ray diffraction
Resolution: 3.45  Å
Source Organism:
Similar Structures:
Biological Unit for 8Y0C: tetrameric; determined by author and by software (PISA)
Molecular Components in 8Y0C
Label Count Molecule
Protein (1 molecule)
1
Crispr-associated Endonuclease Cas12a
Molecule annotation
Nucleotides(3 molecules)
1
RNA (42-mer)
Molecule annotation
1
DNA (27-mer)
Molecule annotation
1
DNA (5'-d(p*ap*gp*tp*cp*cp*tp*tp*tp*ap*cp*t)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303