8XRP: The Cryo-EM structure of IL-12, receptor subunit beta-1 and receptor subunit beta-2 complex

PDB ID: 8XRPDownload
MMDB ID: 250230
PDB Deposition Date: 2024/1/7
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 3.75  Å
Source Organism:
Similar Structures:
Biological Unit for 8XRP: hexadecameric; determined by author and by software
Molecular Components in 8XRP
Label Count Molecule
Proteins (16 molecules)
4
Interleukin-12 Subunit Alpha
(Gene symbol: IL12A)
Molecule annotation
4
Interleukin-12 Subunit Beta
(Gene symbol: IL12B)
Molecule annotation
4
Interleukin-12 Receptor Subunit Beta-2
(Gene symbol: IL12RB2)
Molecule annotation
4
Interleukin-12 Receptor Subunit Beta-1
(Gene symbol: IL12RB1)
Molecule annotation
Chemicals and Non-standard biopolymers (24 molecules)
1
20
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
4
beta-D-mannopyranosebeta-D-mannopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303