8XKR: Cryo-EM structure of human insulin receptor bound to 4 IGF-I, conformation 2

PDB ID: 8XKRDownload
MMDB ID: 257252
PDB Deposition Date: 2023/12/24
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3.53  Å
Source Organism:
Similar Structures:
Molecular Components in 8XKR
Label Count Molecule
Proteins (6 molecules)
4
Insulin-like Growth Factor I
(Gene symbol: IGF1)
Molecule annotation
2
Isoform Short of Insulin Receptor
(Gene symbol: INSR)
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303