8XKO: CryoEM structure of compound HNC-1664 bound with RdRP-RNA complex of SARS-CoV-2

PDB ID: 8XKODownload
MMDB ID: 256005
PDB Deposition Date: 2023/12/23
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3.29  Å
Source Organism:
Severe acute respiratory syndrome coronavirus▼
Similar Structures:
Biological Unit for 8XKO: hexameric; determined by author
Molecular Components in 8XKO
Label Count Molecule
Proteins (4 molecules)
1
RNA-directed RNA Polymerase Nsp12
Molecule annotation
2
Non-structural Protein 8
Molecule annotation
1
Non-structural Protein 7
Molecule annotation
Nucleotides(2 molecules)
1
RNA (5'-r(p*cp*up*ap*cp*gp*cp*gp*up*ap*gp*cp*ap*up*g)-3')
Molecule annotation
1
RNA (5'-r(p*up*up*cp*ap*up*gp*cp*up*ap*cp*gp*cp*gp*up*ap*g)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
Unknown
2
3
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303