8XH9: Human Cx36/GJD2 (Ala14 deletion mutant) gap junction channel prepared with mefloquine, showing no bound mefloquine

PDB ID: 8XH9Download
MMDB ID: 254643
PDB Deposition Date: 2023/12/17
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 2.58  Å
Source Organism:
Similar Structures:
Biological Unit for 8XH9: dodecameric; determined by author
Molecular Components in 8XH9
Label Count Molecule
Proteins (12 molecules)
12
GAP Junction Delta-2 Protein
(Gene symbol: GJD2)
Molecule annotation
Chemicals and Non-standard biopolymers (60 molecules)
1
60
1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303