8XGV: Optimization Efforts for Identification of Novel Highly Potent Keap1-Nrf2 Protein-Protein Interaction (PPI) Inhibitors

PDB ID: 8XGVDownload
MMDB ID: 247373
PDB Deposition Date: 2023/12/15
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 1.42  Å
Source Organism:
Similar Structures:
Biological Unit for 8XGV: monomeric; determined by author and by software
Molecular Components in 8XGV
Label Count Molecule
Protein (1 molecule)
1
Kelch-like Ech-associated Protein 1
(Gene symbol: KEAP1)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
Unknown
2
1
ACETATE IONACETATE ION
3
5
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303