8X94: Structure of human TRPV1 in complex with antagonist --protein purified without CHS

PDB ID: 8X94Download
MMDB ID: 251115
PDB Deposition Date: 2023/11/29
Updated in MMDB: 2025/08
Experimental Method:
electron microscopy
Resolution: 2.55  Å
Source Organism:
Similar Structures:
Biological Unit for 8X94: tetrameric; determined by author
Molecular Components in 8X94
Label Count Molecule
Proteins (4 molecules)
4
Transient Receptor Potential Cation Channel Subfamily V Member 1,green Fluorescent Protein
(Gene symbol: TRPV1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile
2
4
CHOLESTEROLCHOLESTEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303