8X6X: Structure of the multidrug efflux pump EfpA from M. tuberculosis complexed with lipids

PDB ID: 8X6XDownload
MMDB ID: 255706
PDB Deposition Date: 2023/11/22
Updated in MMDB: 2025/12
Experimental Method:
electron microscopy
Resolution: 2.92  Å
Source Organism:
Similar Structures:
Biological Unit for 8X6X: dimeric; determined by author
Molecular Components in 8X6X
Label Count Molecule
Proteins (2 molecules)
2
Uncharacterized Mfs-type Transporter Efpa
(Gene symbol: efpA)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
[(2~{R})-1-[(9~{Z},12~{Z},15~{E})-octadeca-9,12,15-trienoyl]oxy-3-phosphonooxy-propan-2-yl] nonadecanoate[(2~{R})-1-[(9~{Z},12~{Z},15~{E})-octadeca-9,12,15-trienoyl]oxy-3-phosphonooxy-propan-2-yl] nonadecanoate
2
1
[(2~{S})-1-dodecanoyloxy-3-phosphonooxy-propan-2-yl] tridecanoate[(2~{S})-1-dodecanoyloxy-3-phosphonooxy-propan-2-yl] tridecanoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303