8X5Y: CryoEM structure of the histamine H1 receptor-BRIL/Anti BRIL Fab complex with astemizole

PDB ID: 8X5YDownload
MMDB ID: 241537
PDB Deposition Date: 2023/11/20
Updated in MMDB: 2025/07
Experimental Method:
electron microscopy
Resolution: 3  Å
Source Organism:
Similar Structures:
Biological Unit for 8X5Y: monomeric; determined by author
Molecular Components in 8X5Y
Label Count Molecule
Protein (1 molecule)
1
Histamine H1 Receptor,soluble Cytochrome B562
(Gene symbol: HRH1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303