8X3M: Crystal structure of p38alpha with an allosteric inhibitor 2

PDB ID: 8X3MDownload
MMDB ID: 255271
PDB Deposition Date: 2023/11/14
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 8X3M: monomeric; determined by author
Molecular Components in 8X3M
Label Count Molecule
Protein (1 molecule)
1
Mitogen-activated Protein Kinase 14
(Gene symbol: MAPK14)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
~{N}-(5,6-dimethoxy-1,3-benzothiazol-2-yl)-2-[(4-fluoranylphenoxy)methyl]-1,3-thiazole-4-carboxamide~{N}-(5,6-dimethoxy-1,3-benzothiazol-2-yl)-2-[(4-fluoranylphenoxy)methyl]-1,3-thiazole-4-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303