8WYW: Crystal structure of spleen tyrosine kinase (SYK) in complex with SKI-O-592 (free form of SKI-O-703, cevidoplenib)

PDB ID: 8WYWDownload
MMDB ID: 254617
PDB Deposition Date: 2023/10/31
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 8WYW: dimeric; determined by author and by software
Molecular Components in 8WYW
Label Count Molecule
Proteins (2 molecules)
2
Tyrosine-protein Kinase SYK
(Gene symbol: SYK)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
SKI-O-592SKI-O-592
2
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303