8WUZ: Development of 2-imino-2,3,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-4(1H)-one derivatives as human caseinolytic peptidase P (hClpP) activators

PDB ID: 8WUZDownload
MMDB ID: 253953
PDB Deposition Date: 2023/10/22
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 8WUZ: 14-meric; determined by author and by software (PISA)
Molecular Components in 8WUZ
Label Count Molecule
Proteins (14 molecules)
14
Atp-dependent CLP Protease Proteolytic Subunit, Mitochondrial
(Gene symbol: CLPP)
Molecule annotation
Chemicals and Non-standard biopolymers (30 molecules)
1
14
5-[(3-fluorophenyl)methyl]-9-[[4-(trifluoromethyl)phenyl]methyl]-1,5,9,11-tetrazatricyclo[8.4.0.0^{2,7}]tetradeca-2(7),10-dien-8-one5-[(3-fluorophenyl)methyl]-9-[[4-(trifluoromethyl)phenyl]methyl]-1,5,9,11-tetrazatricyclo[8.4.0.0^{2,7}]tetradeca-2(7),10-dien-8-one
2
16
BROMIDE IONBROMIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303