8WQH: cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2)

PDB ID: 8WQHDownload
MMDB ID: 245045
PDB Deposition Date: 2023/10/11
Updated in MMDB: 2024/05
Experimental Method:
electron microscopy
Resolution: 3.44  Å
Source Organism:
Similar Structures:
Biological Unit for 8WQH: dodecameric; determined by author
Molecular Components in 8WQH
Label Count Molecule
Proteins (12 molecules)
2
Cullin-2
(Gene symbol: CUL2)
Molecule annotation
2
E3 Ubiquitin-protein Ligase Rbx1, N-terminally Processed
(Gene symbol: RBX1)
Molecule annotation
2
Elongin-c
(Gene symbol: ELOC)
Molecule annotation
2
Elongin-b
(Gene symbol: ELOB)
Molecule annotation
2
Protein Fem-1 Homolog B
(Gene symbol: FEM1B)
Molecule annotation
2
Coiled-coil Domain-containing Protein 89
(Gene symbol: CCDC89)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
6
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303