8WPM: Cryo-EM structure of the human TRPC1/C4 heteromer in complex with Pico145

PDB ID: 8WPMDownload
MMDB ID: 253630
PDB Deposition Date: 2023/10/10
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 3.43  Å
Source Organism:
Similar Structures:
Biological Unit for 8WPM: tetrameric; determined by author and by software
Molecular Components in 8WPM
Label Count Molecule
Proteins (4 molecules)
1
Short Transient Receptor Potential Channel 1
(Gene symbol: TRPC1)
Molecule annotation
3
Short Transient Receptor Potential Channel 4
(Gene symbol: TRPC4)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
4
7-[(4-chlorophenyl)methyl]-3-methyl-1-(3-oxidanylpropyl)-8-[3-(trifluoromethyloxy)phenoxy]purine-2,6-dione7-[(4-chlorophenyl)methyl]-3-methyl-1-(3-oxidanylpropyl)-8-[3-(trifluoromethyloxy)phenoxy]purine-2,6-dione
2
4
ZINC IONZINC ION
3
3
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303