8WGB: mGlu2-4 heterodimer bound with Gi

PDB ID: 8WGBDownload
MMDB ID: 254189
PDB Deposition Date: 2023/9/20
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3.7  Å
Source Organism:
Similar Structures:
Biological Unit for 8WGB: pentameric; determined by author and by software
Molecular Components in 8WGB
Label Count Molecule
Proteins (5 molecules)
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
(Gene symbol: GNG2)
Molecule annotation
1
Metabotropic Glutamate Receptor 2
(Gene symbol: GRM2)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-3
(Gene symbol: GNAI3)
Molecule annotation
1
Metabotropic Glutamate Receptor 4
(Gene symbol: GRM4)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
GLUTAMIC ACIDGLUTAMIC ACID
2
1
(1R,2S)-2-[[3,5-bis(chloranyl)phenyl]carbamoyl]cyclohexane-1-carboxylic acid(1R,2S)-2-[[3,5-bis(chloranyl)phenyl]carbamoyl]cyclohexane-1-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303