8WEJ: Structure of human phagocyte NADPH oxidase in the activated state

PDB ID: 8WEJDownload
MMDB ID: 241842
PDB Deposition Date: 2023/9/18
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 2.79  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 8WEJ: heptameric; determined by author and by software
Molecular Components in 8WEJ
Label Count Molecule
Proteins (7 molecules)
1
Cytochrome B-245 Light Chain
Molecule annotation
1
Cytochrome B-245 Heavy Chain
Molecule annotation
1
Neutrophil Cytosol Factor 1
Molecule annotation
1
Neutrophil Cytosolic Factor 2 (65kda, Chronic Granulomatous Disease, Autosomal 2), Isoform Cra_a
Molecule annotation
1
RAC Family Small Gtpase 1
Molecule annotation
1
7D5 FAB Heavy Chain
Molecule annotation
1
7D5 FAB Light Chain
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
beta-D-mannopyranosebeta-D-mannopyranose
3
2
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
4
2
MAGNESIUM IONMAGNESIUM ION
5
1
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
6
1
DIHYDROFLAVINE-ADENINE DINUCLEOTIDEDIHYDROFLAVINE-ADENINE DINUCLEOTIDE
7
1
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303