8W9I: Crystal structure of bacterial prolyl-tRNA synthetase in complex with inhibitor PAA-5

PDB ID: 8W9IDownload
MMDB ID: 252186
PDB Deposition Date: 2023/9/5
Updated in MMDB: 2025/09
Experimental Method:
x-ray diffraction
Resolution: 2.45  Å
Source Organism:
Similar Structures:
Biological Unit for 8W9I: dimeric; determined by author and by software (PISA)
Molecular Components in 8W9I
Label Count Molecule
Proteins (2 molecules)
2
Proline--trna Ligase
(Gene symbol: proS)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
2
(2~{S})-~{N}-[3-(4-azanylquinazolin-7-yl)phenyl]sulfonylpyrrolidine-2-carboxamide(2~{S})-~{N}-[3-(4-azanylquinazolin-7-yl)phenyl]sulfonylpyrrolidine-2-carboxamide
2
3
MAGNESIUM IONMAGNESIUM ION
3
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303