8W8R: Cryo-EM structure of the AA-14-bound GPR101-Gs complex

PDB ID: 8W8RDownload
MMDB ID: 240901
PDB Deposition Date: 2023/9/4
Updated in MMDB: 2024/04
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8W8R: pentameric; determined by author
Molecular Components in 8W8R
Label Count Molecule
Proteins (5 molecules)
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1,guanine Nucleotide-binding Protein G(s) Subunit
(Gene symbol: GNAI1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Probable G-protein Coupled Receptor 101
(Gene symbol: GPR101)
Molecule annotation
1
Scfv16
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
(Gene symbol: GNG2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
1-(4-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]thiourea1-(4-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]thiourea
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303