8W5C: Crystal structure of FGFR4 kinase domain in complex with 8K

PDB ID: 8W5CDownload
MMDB ID: 250446
PDB Deposition Date: 2023/8/26
Updated in MMDB: 2025/09
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8W5C: dimeric; determined by author
Molecular Components in 8W5C
Label Count Molecule
Proteins (2 molecules)
2
Fibroblast Growth Factor Receptor 4
(Gene symbol: FGFR4)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-5-methanoyl-6-[(4-methylpiperazin-1-yl)methyl]-1-propan-2-yl-pyrrolo[3,2-b]pyridine-3-carboxamideN-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-5-methanoyl-6-[(4-methylpiperazin-1-yl)methyl]-1-propan-2-yl-pyrrolo[3,2-b]pyridine-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303