8W50: Crystal structure of DNA binding and cleavage core of human topoisomerase 2-alpha in a DNA binding-competent conformation

PDB ID: 8W50Download
MMDB ID: 250205
PDB Deposition Date: 2023/8/25
Updated in MMDB: 2024/07
Experimental Method:
x-ray diffraction
Resolution: 2.67  Å
Source Organism:
Similar Structures:
Biological Unit for 8W50: dimeric; determined by author
Molecular Components in 8W50
Label Count Molecule
Proteins (2 molecules)
2
DNA Topoisomerase 2-alpha
(Gene symbol: TOP2A)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
3
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303