8W4U: human KCNQ2-CaM in complex with PIP2 and HN37

PDB ID: 8W4UDownload
MMDB ID: 239862
PDB Deposition Date: 2023/8/25
Updated in MMDB: 2023/12
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8W4U: octameric; determined by author
Molecular Components in 8W4U
Label Count Molecule
Proteins (8 molecules)
4
Potassium Voltage-gated Channel Subfamily KQT Member 2
(Gene symbol: KCNQ2)
Molecule annotation
4
Calmodulin-1
(Gene symbol: CALM1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
methyl N-[4-[(4-fluorophenyl)methyl-prop-2-ynyl-amino]-2,6-dimethyl-phenyl]carbamatemethyl N-[4-[(4-fluorophenyl)methyl-prop-2-ynyl-amino]-2,6-dimethyl-phenyl]carbamate
2
4
[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303