8W4Q: Crystal structure of PDE4D complexed with CX-4945

PDB ID: 8W4QDownload
MMDB ID: 238926
PDB Deposition Date: 2023/8/24
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.55  Å
Source Organism:
Similar Structures:
Biological Unit for 8W4Q: dimeric; determined by author
Molecular Components in 8W4Q
Label Count Molecule
Proteins (2 molecules)
2
Camp-specific 3',5'-cyclic Phosphodiesterase 4D
(Gene symbol: PDE4D)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
2
ZINC IONZINC ION
3
2
5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid
4
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303