8W49: mouse isocitrate dehydrogenase with isocitrate and magnesium

PDB ID: 8W49Download
MMDB ID: 251794
PDB Deposition Date: 2023/8/23
Updated in MMDB: 2025/09
Experimental Method:
x-ray diffraction
Resolution: 1.77  Å
Source Organism:
Similar Structures:
Biological Unit for 8W49: dimeric; determined by author and by software (PISA)
Molecular Components in 8W49
Label Count Molecule
Proteins (2 molecules)
2
Isocitrate Dehydrogenase [nadp] Cytoplasmic
(Gene symbol: Idh1)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
2
MAGNESIUM IONMAGNESIUM ION
3
2
ISOCITRIC ACIDISOCITRIC ACID
4
4
ISOPROPYL ALCOHOLISOPROPYL ALCOHOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303