8W30: Crystal structure of alpha-V beta-1 integrin headpiece in complex with TR01225179

PDB ID: 8W30Download
MMDB ID: 257465
PDB Deposition Date: 2024/2/21
Updated in MMDB: 2025/01
Experimental Method:
x-ray diffraction
Resolution: 2.45  Å
Source Organism:
Similar Structures:
Biological Unit for 8W30: dimeric; determined by author and by software (PISA)
Molecular Components in 8W30
Label Count Molecule
Proteins (2 molecules)
1
Integrin Alpha-v Heavy Chain
(Gene symbol: ITGAV)
Molecule annotation
1
Integrin Beta-1
(Gene symbol: ITGB1)
Molecule annotation
Chemicals and Non-standard biopolymers (21 molecules)
1
9
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
beta-D-mannopyranosebeta-D-mannopyranose
3
3
alpha-D-mannopyranosealpha-D-mannopyranose
4
6
CALCIUM IONCALCIUM ION
5
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303