8W2R: HIV-1 P5-IN intasome core

PDB ID: 8W2RDownload
MMDB ID: 245567
PDB Deposition Date: 2024/2/21
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.23  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8W2R: dodecameric; determined by author and by software
Molecular Components in 8W2R
Label Count Molecule
Proteins (8 molecules)
8
Integrase
Molecule annotation
Nucleotides(4 molecules)
2
DNA (5'-d(*ap*cp*tp*gp*cp*tp*ap*gp*ap*gp*ap*tp*tp*tp*tp*cp*cp*cp*g)-3')
Molecule annotation
2
DNA (5'-d(p*cp*gp*gp*gp*ap*ap*ap*ap*tp*cp*tp*cp*tp*ap*gp*cp*a)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
2
ZINC IONZINC ION
3
2
(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303