8W0I: Cryo-EM structure of the human MCM2-7 heterohexamer

PDB ID: 8W0IDownload
MMDB ID: 253009
PDB Deposition Date: 2024/2/13
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3.5  Å
Source Organism:
Similar Structures:
Biological Unit for 8W0I: hexameric; determined by author
Molecular Components in 8W0I
Label Count Molecule
Proteins (6 molecules)
1
DNA Replication Licensing Factor Mcm2
(Gene symbol: MCM2)
Molecule annotation
1
DNA Replication Licensing Factor Mcm3
(Gene symbol: MCM3)
Molecule annotation
1
DNA Replication Licensing Factor Mcm4
(Gene symbol: MCM4)
Molecule annotation
1
DNA Replication Licensing Factor Mcm5
(Gene symbol: MCM5)
Molecule annotation
1
DNA Replication Licensing Factor Mcm6
(Gene symbol: MCM6)
Molecule annotation
1
DNA Replication Licensing Factor Mcm7
(Gene symbol: MCM7)
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
5
ZINC IONZINC ION
2
5
MAGNESIUM IONMAGNESIUM ION
3
4
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
4
1
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303