8W0E: Cryo-EM structure of a human MCM2-7 single hexamer on dsDNA

PDB ID: 8W0EDownload
MMDB ID: 253006
PDB Deposition Date: 2024/2/13
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3.4  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 8W0E: octameric; determined by author
Molecular Components in 8W0E
Label Count Molecule
Proteins (6 molecules)
1
DNA Replication Licensing Factor Mcm2
Molecule annotation
1
DNA Replication Licensing Factor Mcm3
Molecule annotation
1
DNA Replication Licensing Factor Mcm4
Molecule annotation
1
DNA Replication Licensing Factor Mcm5
Molecule annotation
1
DNA Replication Licensing Factor Mcm6
Molecule annotation
1
DNA Replication Licensing Factor Mcm7
Molecule annotation
Nucleotides(2 molecules)
1
DNA (25-mer)
Molecule annotation
1
DNA (25-mer)
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
5
ZINC IONZINC ION
2
5
MAGNESIUM IONMAGNESIUM ION
3
1
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
4
4
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303