8W03: Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-1154

PDB ID: 8W03Download
MMDB ID: 248281
PDB Deposition Date: 2024/2/13
Updated in MMDB: 2024/06
Experimental Method:
x-ray diffraction
Resolution: 1.68  Å
Source Organism:
Similar Structures:
Biological Unit for 8W03: dimeric; determined by author and by software (PISA)
Molecular Components in 8W03
Label Count Molecule
Proteins (2 molecules)
2
Estrogen Receptor
(Gene symbol: ESR1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
(1S,2R,4S)-N-(4-chlorophenyl)-5,6-bis(4-hydroxyphenyl)-N-(2,2,2-trifluoroethyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide(1S,2R,4S)-N-(4-chlorophenyl)-5,6-bis(4-hydroxyphenyl)-N-(2,2,2-trifluoroethyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303