8VZB: Crystal Structure of 2-Hydroxacyl-CoA Lyase/Synthase ApbHACS from Alphaproteobacteria bacterium in the Complex with THDP, D-Lactyl-CoA, and ADP

PDB ID: 8VZBDownload
MMDB ID: 252997
PDB Deposition Date: 2024/2/11
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.98  Å
Source Organism:
Similar Structures:
Biological Unit for 8VZB: tetrameric; determined by author and by software (PISA)
Molecular Components in 8VZB
Label Count Molecule
Proteins (4 molecules)
4
Oxalyl-coa Decarboxylase
Molecule annotation
Chemicals and Non-standard biopolymers (41 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
4
2-[(2R)-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2-oxidanyl-2H-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate2-[(2R)-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2-oxidanyl-2H-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate
3
4
S-{(3S,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5,10,14-tetraoxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (2R)-2-hydroxypropanethioateS-{(3S,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5,10,14-tetraoxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (2R)-2-hydroxypropanethioate
4
4
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
5
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
6
1
ACETIC ACIDACETIC ACID
7
13
PHOSPHATE IONPHOSPHATE ION
8
2
CHLORIDE IONCHLORIDE ION
9
2
ACETYL GROUPACETYL GROUP
10
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303