8VTQ: Crystal Structure of human Tryptophan 2,3-dioxygenase in complex with PPN3 inhibitor

PDB ID: 8VTQDownload
MMDB ID: 251307
PDB Deposition Date: 2024/1/26
Updated in MMDB: 2024/09
Experimental Method:
x-ray diffraction
Resolution: 2.05  Å
Source Organism:
Similar Structures:
Biological Unit for 8VTQ: tetrameric; determined by author and by software (PISA)
Molecular Components in 8VTQ
Label Count Molecule
Proteins (4 molecules)
4
Tryptophan 2,3-dioxygenase
(Gene symbol: TDO2)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
4
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
4
alpha-methyl-L-tryptophanalpha-methyl-L-tryptophan
3
4
alpha-methyl-L-tryptophanalpha-methyl-L-tryptophan
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303