8VHE: Crystal Structure of Human IDH1 R132Q in Complex with NADPH-TCEP Adduct

PDB ID: 8VHEDownload
MMDB ID: 245946
PDB Deposition Date: 2023/12/31
Updated in MMDB: 2025/05
Experimental Method:
x-ray diffraction
Resolution: 2.16  Å
Source Organism:
Similar Structures:
Biological Unit for 8VHE: dimeric; determined by author and by software (PISA)
Molecular Components in 8VHE
Label Count Molecule
Proteins (2 molecules)
2
Isocitrate Dehydrogenase [nadp] Cytoplasmic
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
2
Unknown
2
6
GLYCEROLGLYCEROL
3
2
CHLORIDE IONCHLORIDE ION
4
2
CALCIUM IONCALCIUM ION
5
1
THIOCYANATE IONTHIOCYANATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303