8VH5: Cryo-EM structure of Rab12-LRRK2 complex in the LRRK2 dimer state

PDB ID: 8VH5Download
MMDB ID: 253265
PDB Deposition Date: 2023/12/30
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 4  Å
Source Organism:
Similar Structures:
Biological Unit for 8VH5: tetrameric; determined by author
Molecular Components in 8VH5
Label Count Molecule
Proteins (4 molecules)
2
Leucine-rich Repeat Serine/threonine-protein Kinase 2
(Gene symbol: LRRK2)
Molecule annotation
2
Ras-related Protein Rab-12
(Gene symbol: RAB12)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
2
2
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
3
2
MAGNESIUM IONMAGNESIUM ION
4
2
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303