8VBY: Structure of the human dopamine transporter in complex with beta-CFT, MRS7292 and divalent zinc

PDB ID: 8VBYDownload
MMDB ID: 250739
PDB Deposition Date: 2023/12/12
Updated in MMDB: 2024/09
Experimental Method:
electron microscopy
Resolution: 3.19  Å
Source Organism:
Similar Structures:
Biological Unit for 8VBY: monomeric; determined by author and by software
Molecular Components in 8VBY
Label Count Molecule
Protein (1 molecule)
1
Sodium-dependent Dopamine Transporter
(Gene symbol: SLC6A3)
Molecule annotation
Chemicals and Non-standard biopolymers (41 molecules)
1
1
methyl (1R,2S,3S,5S)-3-(4-fluorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylatemethyl (1R,2S,3S,5S)-3-(4-fluorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
2
1
methyl (1R,2S,3S,5S)-3-(4-fluorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylatemethyl (1R,2S,3S,5S)-3-(4-fluorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
3
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
4
4
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
5
8
DECANEDECANE
6
7
PENTANEPENTANE
7
8
HEPTANEHEPTANE
8
1
ZINC IONZINC ION
9
1
SODIUM IONSODIUM ION
10
6
DODECANEDODECANE
11
1
PENTADECANEPENTADECANE
12
2
N-OCTANEN-OCTANE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303