8VA6: Menin in complex with Ziftomenib (KO-539)

PDB ID: 8VA6Download
MMDB ID: 255254
PDB Deposition Date: 2023/12/11
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.57  Å
Source Organism:
Similar Structures:
Biological Unit for 8VA6: monomeric; determined by author
Molecular Components in 8VA6
Label Count Molecule
Protein (1 molecule)
1
Menin
(Gene symbol: MEN1)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
1
ZiftomenibZiftomenib
2
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
3
3
SULFATE IONSULFATE ION
4
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
5
2
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
6
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303