8V8C: Alpha7-nicotinic acetylcholine receptor time resolved bound to epibatidine and PNU-120596 asymmetric state 1

PDB ID: 8V8CDownload
MMDB ID: 243125
PDB Deposition Date: 2023/12/5
Updated in MMDB: 2025/06
Experimental Method:
electron microscopy
Resolution: 3.29  Å
Source Organism:
Similar Structures:
Biological Unit for 8V8C: pentameric; determined by author
Molecular Components in 8V8C
Label Count Molecule
Proteins (5 molecules)
5
Neuronal Acetylcholine Receptor Subunit Alpha-7,soluble Cytochrome B562
(Gene symbol: CHRNA7)
Molecule annotation
Chemicals and Non-standard biopolymers (33 molecules)
1
20
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
5
EPIBATIDINEEPIBATIDINE
3
5
N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-ureaN-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea
4
3
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303