8V2L: Crystal structure of IRAK4 kinase domain with compound 8

PDB ID: 8V2LDownload
MMDB ID: 249267
PDB Deposition Date: 2023/11/22
Updated in MMDB: 2024/07
Experimental Method:
x-ray diffraction
Resolution: 2.43  Å
Source Organism:
Similar Structures:
Biological Unit for 8V2L: monomeric; determined by author
Molecular Components in 8V2L
Label Count Molecule
Protein (1 molecule)
1
Interleukin-1 Receptor-associated Kinase 4
(Gene symbol: IRAK4)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
N-{2-[4-(hydroxymethyl)phenyl]-6-(2-hydroxypropan-2-yl)-2H-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamideN-{2-[4-(hydroxymethyl)phenyl]-6-(2-hydroxypropan-2-yl)-2H-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303