8V1F: TMPRSS2 complexed with the noncovalent inhibitor 6-amidino-2-napthol

PDB ID: 8V1FDownload
MMDB ID: 242441
PDB Deposition Date: 2023/11/20
Updated in MMDB: 2024/02
Experimental Method:
x-ray diffraction
Resolution: 2.19  Å
Source Organism:
Similar Structures:
Biological Unit for 8V1F: dimeric; determined by author and by software (PISA)
Molecular Components in 8V1F
Label Count Molecule
Proteins (2 molecules)
1
Transmembrane Protease Serine 2 Non-catalytic Chain
(Gene symbol: TMPRSS2)
Molecule annotation
1
Transmembrane Protease Serine 2
(Gene symbol: TMPRSS2)
Molecule annotation
Chemicals and Non-standard biopolymers (19 molecules)
1
1
2-acetamido-2-deoxy-beta-D-glucopyranose (Link to PubChem not yet available)2-acetamido-2-deoxy-beta-D-glucopyranose
2
3
TRIS(HYDROXYETHYL)AMINOMETHANE (Link to PubChem not yet available)TRIS(HYDROXYETHYL)AMINOMETHANE
3
1
UNKNOWN ATOM OR ION (Link to PubChem not yet available)UNKNOWN ATOM OR ION
4
12
1,2-ETHANEDIOL (Link to PubChem not yet available)1,2-ETHANEDIOL
5
1
6-oxidanylnaphthalene-2-carboximidamide (Link to PubChem not yet available)6-oxidanylnaphthalene-2-carboximidamide
6
1
TETRAETHYLENE GLYCOL (Link to PubChem not yet available)TETRAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303