8V0C: Structure of TDP1 catalytic domain complexed with compound IB06

PDB ID: 8V0CDownload
MMDB ID: 252686
PDB Deposition Date: 2023/11/17
Updated in MMDB: 2024/09
Experimental Method:
x-ray diffraction
Resolution: 1.62  Å
Source Organism:
Similar Structures:
Biological Unit for 8V0C: monomeric; determined by author
Molecular Components in 8V0C
Label Count Molecule
Protein (1 molecule)
1
Tyrosyl-dna Phosphodiesterase 1
(Gene symbol: TDP1)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
(8M)-8-(2-{[2-(fluorosulfonyl)ethyl]amino}phenyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(8M)-8-(2-{[2-(fluorosulfonyl)ethyl]amino}phenyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
3
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
4
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303