8V0B: Structure of TDP1 catalytic domain complexed with compound IB05

PDB ID: 8V0BDownload
MMDB ID: 252685
PDB Deposition Date: 2023/11/17
Updated in MMDB: 2024/09
Experimental Method:
x-ray diffraction
Resolution: 1.65  Å
Source Organism:
Similar Structures:
Biological Unit for 8V0B: monomeric; determined by author
Molecular Components in 8V0B
Label Count Molecule
Protein (1 molecule)
1
Tyrosyl-dna Phosphodiesterase 1
(Gene symbol: TDP1)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
1
8-{4-[(fluorosulfonyl)oxy]phenyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid8-{4-[(fluorosulfonyl)oxy]phenyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
2
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303