8V04: High resolution TMPRSS2 structure following acylation by nafamostat

PDB ID: 8V04Download
MMDB ID: 242149
PDB Deposition Date: 2023/11/16
Updated in MMDB: 2024/02
Experimental Method:
x-ray diffraction
Resolution: 1.58  Å
Source Organism:
Similar Structures:
Biological Unit for 8V04: dimeric; determined by author and by software (PISA)
Molecular Components in 8V04
Label Count Molecule
Proteins (2 molecules)
1
Transmembrane Protease Serine 2 Non-catalytic Chain
(Gene symbol: TMPRSS2)
Molecule annotation
1
Transmembrane Protease Serine 2
(Gene symbol: TMPRSS2)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
3
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
alpha-L-fucopyranosealpha-L-fucopyranose
3
9
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
UNKNOWN ATOM OR ION (Link to PubChem not yet available)UNKNOWN ATOM OR ION
5
1
4-carbamimidamidobenzoic acid4-carbamimidamidobenzoic acid
6
1
CITRIC ACIDCITRIC ACID
7
1
CALCIUM IONCALCIUM ION
8
1
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303